Product Description: hOAT-IN-1 (compound 5) is a mechanical inhibitor of human ornithine aminotransferase (hOAT). hOAT-IN-1 as a time-dependent inhibitor can form tightly bound PLP inhibitor adduct with hOAT. hOAT-IN-1 can result IN tight occupation of the active site of hOAT. hOAT-IN-1 can be used in the study of lung cell carcinoma [1].
Formula: C7H9F2NO2
References: [1]Devitt A N, et al. Design, Synthesis, and Mechanistic Studies of (R)-3-Amino-5, 5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase[J]. ACS Chemical Biology, 2024.
Molecular Weight: 177.15
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Others