Product Description: HWY-289 is a semisynthetic protoberberine derivative, has broad-spectrum and potent activities against phytopathogenic fungi, particularly Botrytis cinerea (EC50 = 1.34 μg/mL). HWY-289 changes the morphology of the mycelium and the internal structure of cells. HWY-289 reduces ATP content, ATPase activities, and key enzyme activities in the TCA cycle[1].
Formula: C31H32BrNO4
References: [1]An JX, et al. Antifungal Activity and Putative Mechanism of HWY-289, a Semisynthetic Protoberberine Derivative, against Botrytis cinerea. J Agric Food Chem. 2024 Apr 10;72(14):7716-7726.
CAS Number: 908001-51-4
Molecular Weight: 562.49
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Fungal