Idebenone (Standard), CAS 58186-27-9

Product Description: Idebenone (Standard) is the analytical standard of Idebenone. This product is intended for research and analytical applications. Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 μM)[1]. Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells[2]. Idebenone quickly crosses the blood-brain barrier.

Formula: N/A

References: [1]G Civenni, et al. Inhibitory effect of the neuroprotective agent idebenone on arachidonic acid metabolism in astrocytes.Eur J Pharmacol. 1999 Apr 9;370(2):161-7./[2]Kwok-Keung Tai, et al. Idebenone induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells. Neurotox Res. 2011 Nov;20(4):321-8.

CAS Number: 58186-27-9

Molecular Weight: N/A

Research Area: Neurological Disease

Target: Apoptosis;Mitochondrial Metabolism

• Artikelnummer: MEXHY-N0303R-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N0303R-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK