Iguratimod (Standard), CAS 123663-49-0

Product Description: Iguratimod (Standard) is the analytical standard of Iguratimod. This product is intended for research and analytical applications. Iguratimod is an antirheumatic agent, acts as an inhibitor of COX-2, with an IC50 of 20 μM (7.7 μg/mL), but shows no effect on COX-1. Iguratimod also inhibits macrophage migration inhibitory factor (MIF) with an IC50 of 6.81 μM.

Formula: N/A

References: [1]Tanaka K, et al. T-614, a novel antirheumatic drug, inhibits both the activity and induction of cyclooxygenase-2 (COX-2) in cultured fibroblasts. Jpn J Pharmacol. 1995 Apr;67(4):305-14./[2]Sun Y, et al. Anti-rheumatic drug iguratimod protects against cancer-induced bone pain and bone destruction in a rat model. Oncol Lett. 2017 Jun;13(6):4849-4856./[3]Iguratimod, et al. Identification of Iguratimod as an Inhibitor of Macrophage Migration Inhibitory Factor (MIF) with Steroid-sparing Potential. J Biol Chem. 2016 Dec 16;291(51):26502-26514.

CAS Number: 123663-49-0

Molecular Weight: N/A

Research Area: Inflammation/Immunology

Target: COX;Macrophage migration inhibitory factor (MIF)

• Artikelnummer: MEXHY-17009R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-17009R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK