Illudalic acid, CAS 18508-77-5

Illudalic acid, CAS 18508-77-5
Artikelnummer
MEXHY-N12776-0
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MedChemExpress

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Product Description: Illudalic acid is a potent and selective Leukocyte antigen-related (LAR) phosphatase inhibitor with an IC50 value of 1.30 µM. Illudalic acid inhibits LAR phosphatase through covalent ligation to the catalytic cysteine residue[1][2].

Formula: C15H16O5

References: [1]Hansen DT, et al. The mechanism of covalent inhibition of LAR phosphatase by illudalic acid. Bioorg Med Chem Lett. 2024 May 15;104:129740./[2]Ling Q, et al. Illudalic acid as a potential LAR inhibitor: synthesis, SAR, and preliminary studies on the mechanism of action. Bioorg Med Chem. 2008 Aug 1;16(15):7399-409.

CAS Number: 18508-77-5

Molecular Weight: 276.28

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Phosphatase
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Artikelnummer MEXHY-N12776-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-N12776-0
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