Product Description: IM-250 is an orally active helicase-primase inhibitor. IM-250 is effective against HSV infection. IM-250 inhibits HSV-1 infection in Vero cells (IC50: ~20 nM)[1][2].
Formula: C20H19F2N3O2S2
References: [1]Bernstein DI, et al. Intermittent therapy with helicase-primase inhibitor IM-250 efficiently controls recurrent herpes disease and reduces reactivation of latent HSV. Antiviral Res. 2023 Nov;219:105733. /[2]Uhlig N, et al. Helicase primase inhibitors (HPIs) are efficacious for therapy of human herpes simplex virus (HSV) disease in an infection mouse model. Antiviral Res. 2021 Nov;195:105190.