Imepitoin, CAS 188116-07-6

Product Description: Imepitoin (AWD 131-138) is a new low-affinity partial benzodiazepine receptor agonist with potent anticonvulsant and anxiolytic properties in rodent models.

Applications: Neuroscience-Neuromodulation

Formula: C13H14ClN3O2

References: [1]Sigel E, et al. The antiepileptic drug AWD 131-138 stimulates different recombinant isoforms of the rat GABA(A) receptor through the benzodiazepine binding site. Neurosci Lett. 1998 Apr 3;245(2):85-8./[2]Yasar S, et al. Evaluation of the novel antiepileptic drug, AWD 131-138, for benzodiazepine-like discriminative stimulus and reinforcing effects in squirrel monkeys. Eur J Pharmacol. 2003 Apr 4;465(3):257-65./[3]Loscher W, et al. Anticonvulsant efficacy of the low-affinity partial benzodiazepine receptor agonist ELB 138 in a dog seizure model and in epileptic dogs with spontaneously recurrent seizures. Epilepsia. 2004 Oct;45(10):1228-39.

CAS Number: 188116-07-6

Molecular Weight: 279.72

Compound Purity: 99.43

Research Area: Neurological Disease

Solubility: DMSO : 12.5 mg/mL (ultrasonic)

Target: GABA Receptor

• Artikelnummer: MEXHY-14953-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-14953-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK