Product Description: INY-05-040 is a AKT degrader that can selectively and quickly degrade all three AKT isoforms. INY-05-040 can inhibit downstream signaling and cell proliferation in 288 cancer cell lines, with anti-cancer activity[1].
Applications: Cancer-Kinase/protease
Formula: C55H76ClN9O6S
References: [1]Erickson E C, et al. Multi-omic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation[J]. bioRxiv, 2022: 2022.10. 11.511726./[2]Erickson E C, et al. Multi-omic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation[J]. bioRxiv, 2022: 2022.10. 11.511726.
CAS Number: 2503018-29-7
Molecular Weight: 1026.77
Compound Purity: 95.70
Research Area: Cancer
Solubility: DMSO : ≥ 100 mg/mL
Target: Akt;PROTACs