Itaconic acid (Standard), CAS 97-65-4

Product Description: Itaconic acid (Standard) is the analytical standard of Itaconic acid. This product is intended for research and analytical applications. Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. Itaconic acid has anti-inflammatory, anti-microbial and immunomodulatory effect[1][2][4][5].

Formula: C5H6O4

References: [1]Weiss JM, et, al. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. J Clin Invest. 2018 Aug 31;128(9):3794-3805./[2]Zhao M, et, al. Itaconic acid production in microorganisms. Biotechnol Lett. 2018 Mar;40(3):455-464./[3]Qu C, et al. Itaconic acid induces ferroptosis by activating ferritinophagy. Biochem Biophys Res Commun. 2021 Oct 25;583:56-62. /[4]Zhu X, et al. Itaconic acid exerts anti-inflammatory and antibacterial effects via promoting pentose phosphate pathway to produce ROS. Sci Rep. 2021 Sep 13;11(1):18173./[5]Umbrasas D, et al. Effects of itaconic acid on neuronal viability and brain mitochondrial functions. J Bioenerg Biomembr. 2021 Oct;53(5):499-511.

CAS Number: 97-65-4

Molecular Weight: 130.10

Research Area: Inflammation/Immunology

Solubility: H2O : 27.78 mg/mL (ultrasonic)

Target: Endogenous Metabolite;Ferroptosis

• Artikelnummer: MEXHY-Y0520R-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-Y0520R-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK