J208, CAS 2116468-11-0

Product Description: J208 is a dual inhibitor for histone deacetylase (HDAC) and DNA methyltransferase (DNMT). J208 inhibits proliferation of cancer cells, as well as the migration/invasion of triple-negative breast cancer (TNBC) cells. J208 induces apoptosis, arrests the cell cycle at G0/G1 phase. J2008 activates the innate immune signalling pathway in TNBC, by inducing the expression of endogenous retroviruses (ERVs)[1].

Applications: COVID-19-anti-virus

Formula: C20H24N6O4

References: [1]Fan W, et al., Bifunctional HDAC and DNMT inhibitor induces viral mimicry activates the innate immune response in triple-negative breast cancer. Eur J Pharm Sci. 2024 Jun 1;197:106767.

CAS Number: 2116468-11-0

Molecular Weight: 412.44

Research Area: Cancer; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Apoptosis;DNA Methyltransferase;HDAC

• Artikelnummer: MEXHY-163535-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-163535-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK