Product Description: JNK-IN-11 (compound 1) is a potent JNK inhibitor with an IC50 value of 2.2, 21.4, 1.8 µM for JNK1, JNK2, JNK3, respectively. JNK-IN-11 has the potential for the research of alzheimer and parkinson disease[1].
Applications: Neuroscience-Neurodegeneration
Formula: C12H11NO3S2
References: [1]Hom RK, et al. Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7303-7.
CAS Number: 676594-38-0
Molecular Weight: 281.35
Compound Purity: 98.01
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: JNK