Ki 23057, CAS 516523-31-2

Product Description: Ki 23057 is a competitive, orally active inhibitor for tyrosine kinase, which inhibits the phosphorylation of K-samII/FGF-R2, VEGF-R1, VEGF-R2, PDGF-Rβ and c-Kit, with IC50s of 88, 69, 83, 100 and 480 nM. Ki 23057 inhibits the proliferation of sclerogastric cancer cells OCUM-2MD3 and OCUM-8, and induces apoptosis. Ki 23057 exhibits antitumor efficacy in mouse models[1].

Formula: C30H35N3O4

References: [1]Nakamura K, et al., A novel molecular targeting compound as K-samII/FGF-R2 phosphorylation inhibitor, Ki23057, for Scirrhous gastric cancer. Gastroenterology. 2006 Nov;131(5):1530-41.

CAS Number: 516523-31-2

Molecular Weight: 501.62

Research Area: Cancer

Target: Apoptosis

• Artikelnummer: MEXHY-18187-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-18187-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK