Description: L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87 glioma cell invasion into a collagen matrix.
CAS Number: 2922-83-0
Formula: C10H12N2O3
Molecular Weight: 208,21
References: Kolho K L , Pessia A , Jaakkola T , et al. Faecal and serum metabolomics in paediatric inflammatory bowel disease[J]. Journal of Crohns & Colitis, 2017, 11(3):321-334.