Lacidipine (Standard), CAS 103890-78-4

Product Description: Lacidipine (Standard) is the analytical standard of Lacidipine. This product is intended for research and analytical applications. Lacidipine is an orally active and highly selective L-type calcium channel blocker that acts on smooth muscle calcium channels, primarily dilates peripheral arteries, reduces peripheral resistance, and has long-lasting anti-hypertensive activity. Lacidipine protects HKCs from apoptosis induced by ATP depletion and recovery by modulating the caspase-3 pathway. Lacidipine can be used in studies of hypertension, atherosclerosis and acute kidney injury (AKI)[1][2].

Formula: N/A

References: [1]Zhang A, et al. Lacidipine attenuates apoptosis via a caspase-3 dependent pathway in human kidney cells. Cell Physiol Biochem. 2013;32(4):1040-9. /[2]Cristofori P, et al. The calcium-channel blocker lacidipine reduces the development of atherosclerotic lesions in the apoE-deficient mouse. J Hypertens. 2000 Oct;18(10):1429-36.

CAS Number: 103890-78-4

Molecular Weight: N/A

Research Area: Cardiovascular Disease

Target: Apoptosis;Calcium Channel;Caspase;Reactive Oxygen Species

• Artikelnummer: MEXHY-B0347R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0347R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK