Lapatinib, CAS 231277-92-2

Description: Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity. Lapatinib has antitumor activity and can be used to treat advanced or metastatic breast cancer with HER2 overexpression.

CAS Number: 231277-92-2

Formula: C29H26ClFN4O4S

Molecular Weight: 581,06

References: Wainberg ZA, et al. Lapatinib, a dual EGFR and HER2 kinase inhibitor, selectively inhibits HER2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo. Clin Cancer Res. 2010 Mar 1;16(5):1509-19.

• Artikelnummer: TGMT0078-50mg
• Hersteller: TargetMol Chemicals
• Hersteller Artikelnummer: T0078-50mg
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK