LASSBio-2052, CAS 2549160-15-6

Product Description: LASSBio-2052 is a derivative of N-acylhydrazone with antitumor activity against hepatocellular carcinoma (HCC). LASSBio-2052 inhibits HCC cells HepG2 and Hep3B, with IC50 of 18 and 41 μM. LASSBio-2052 arrests the cell cycle at G2/M phase, through downregulation of FOXM1. LASSBio-2052 induces apoptosis in HCC cells[1].

Formula: C23H20F3N3O3

References: [1]Andrade AAR, et al., Antiproliferative Activity of N-Acylhydrazone Derivative on Hepatocellular Carcinoma Cells Involves Transcriptional Regulation of Genes Required for G2/M Transition. Biomedicines. 2024 Apr 18;12(4):892.

CAS Number: 2549160-15-6

Molecular Weight: 443.42

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Others

• Artikelnummer: MEXHY-161617-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161617-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK