Product Description: LIH383 is an agonist of ACKR3 (CXCR7) (EC50=0.61 nM). LIH383 efficiently induces the recruitment of β-arrestin to ACKR3 but does not trigger typical G protein signaling[1].
Formula: C45H72N16O8S
References: [1]Meyrath M, et al. The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides. Nat Commun. 2020 Jun 19;11(1):3033.
CAS Number: 2866266-58-0
Molecular Weight: 997.22
Research Area: Inflammation/Immunology; Neurological Disease