LKY-047, CAS 1954681-29-8

Product Description: LKY-047, a Decursin derivative, is a potent and selective reversible competitive cytochrome P45022J2 (CYP2J2) inhibitor with an IC50 of 1.7 μM. LKY-047 is inactive against other human P450s, such as CYPs 1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1, and 3A[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C23H19NO7

References: [1]Nguyen Minh Phuc, et al. LKY-047: First Selective Inhibitor of Cytochrome P450 2J2. Drug Metab Dispos. 2017 Jul;45(7):765-769.

CAS Number: 1954681-29-8

Molecular Weight: 421.40

Compound Purity: 98.85

Research Area: Metabolic Disease; Inflammation/Immunology

Solubility: DMSO : 16.67 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Cytochrome P450

• Artikelnummer: MEXHY-117026-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-117026-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK