Lobeline (hydrochloride) (Standard), CAS 134-63-4

Product Description: Lobeline (hydrochloride) (Standard) is the analytical standard of Lobeline (hydrochloride). This product is intended for research and analytical applications. Lobeline (α-Lobeline) hydrochloride is a brain-penetrant nicotinic receptor agonist. Lobeline hydrochloride increases dopamine (DA) release by inhibiting DA uptake into synaptic vesicles, and altering presynaptic DA storage. Lobeline hydrochloride is effective in smoking cessation[1][2].

Formula: N/A

References: [1]Teng L, et al. Lobeline and nicotine evoke [3H]overflow from rat striatal slices preloaded with [3H]dopamine: differential inhibition of synaptosomal and vesicular [3H]dopamine uptake. J Pharmacol Exp Ther. 1997 Mar;280(3):1432-44. /[2]Monzurul Amin Roni, et al. Lobeline attenuates ethanol abstinence-induced depression-like behavior in mice. Alcohol. 2017 Jun:61:63-70./[3]Harrod SB, et al. Lobeline attenuates d-methamphetamine self-administration in rats. J Pharmacol Exp Ther. 2001 Jul;298(1):172-9.

CAS Number: 134-63-4

Molecular Weight: N/A

Research Area: Neurological Disease

Target: Dopamine Transporter;nAChR

• Artikelnummer: MEXHY-B0979R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0979R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK