Mavacamten (Standard), CAS 1642288-47-8

Product Description: Mavacamten (Standard) is the analytical standard of Mavacamten. This product is intended for research and analytical applications. Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.

Formula: N/A

References: [1]Kawas RF, et al. A small-molecule modulator of cardiac myosin acts on multiple stages of the myosin chemomechanical cycle. J Biol Chem. 2017 Oct 6;292(40):16571-16577./[2]Stern JA, et al. A Small Molecule Inhibitor of Sarcomere Contractility Acutely Relieves Left Ventricular Outflow Tract Obstruction in Feline Hypertrophic Cardiomyopathy. PLoS One. 2016 Dec 14;11(12):e0168407./[3]Green EM, et al. A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice. Science. 2016 Feb 5;351(6273):617-21.

CAS Number: 1642288-47-8

Molecular Weight: N/A

Research Area: Cardiovascular Disease

Target: Myosin

• Artikelnummer: MEXHY-109037R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-109037R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK