Product Description: MBL-IN-3 (compound 72922413) is a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor(IC50=54±4 μM). MBL-IN-3 is identified and shown to lower minimum inhibitory concentrations (MICs) of Meropenem (HY-13678) for a panel of E. coli and K. pneumoniae clinical isolates expressing NDM-1. MBL-IN-3 can be used for antibiotic sensitizer research[1].
Formula: C18H21N3O5
References: [1]Cheng Z, et al. Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase[J]. Journal of Chemical Information and Modeling, 2024.