Product Description: Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity[1]sup>[2].
Applications: Cancer-programmed cell death
Formula: C32H46O7
References: [1]Takiguchi Y, et al. Milbemycins, a new family of macrolide antibiotics: fermentation, isolation and physico-chemical properties. J Antibiot (Tokyo). 1980 Oct;33(10):1120-7./[2]Li J, et al. Isolation and identification of new macrocyclic lactones from a genetically engineered strain Streptomyces bingchenggensis BCJ60. J Antibiot (Tokyo). 2017 Mar;70(3):297-300.
CAS Number: 51596-11-3
Molecular Weight: 542.70
Compound Purity: 99.13
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Antibiotic;P-glycoprotein