ML-211, CAS 2205032-89-7

Product Description: ML-211 is a carbamate-based dual inhibitor of acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) (IC50=17 nM) and LYPLA2 (IC50=30 nM). ML-211 also inhibits theserine hydrolase ABHD11 with an IC50 value of 10 nM but is ≥ 50-fold selective for LYPLA in a panel of 20 additional serine hydrolases[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C25H30N4O2

References: [1]Adibekian, A., Martin, B.R., Speers, A.E., et al. Optimization and characterization of a triazole urea dual inhibitor for lysophospholipase 1 (LYPLA1) and lysophospholipase 2 (LYPLA2). Probe Reports from the NIH Molecular Libraries Program 1 R01 CA132630, 1-42 (2013).

CAS Number: 2205032-89-7

Molecular Weight: 418.53

Compound Purity: 97.0

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: MAGL;Phospholipase

• Artikelnummer: MEXHY-128035-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-128035-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK