Monepantel, CAS 887148-69-8

Product Description: Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.

Applications: Cancer-programmed cell death

Formula: C20H13F6N3O2S

References: [1]Hess J, et al. Assessment of the nematocidal activity of metallocenyl analogues of monepantel. Dalton Trans. 2016 Nov 28;45(44):17662-17671/[2]Raza A, et al. Increased expression of ATP binding cassette transporter genes following exposure of Haemonchus contortus larvae to a high concentration of monepantel in vitro. Parasit Vectors. 2016 Sep 29;9(1):522./[3]Stuchlikova, et al. Monepantel induces hepatic cytochromes p450 in sheep in vitro and in vivo. Chem Biol Interact. 2015 Feb 5;227:63-8. ?/[4]Bahrami F, et al. Monepantel induces autophagy in human ovarian cancer cells through disruption of the mTOR/p70S6K signalling pathway. Am J Cancer Res. 2014 Sep 6;4(5):558-71.

CAS Number: 887148-69-8

Molecular Weight: 473.39

Compound Purity: 99.95

Research Area: Cancer

Solubility: DMSO : ≥ 100 mg/mL

Target: nAChR

• Artikelnummer: MEXHY-14774-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-14774-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK