mPGES1-IN-7, CAS 1268709-57-4

Product Description: mPGES-1-IN-2 (compound III) is a benzimidazole-based mPGES-1 inhibitor that also inhibits adipophysin PGD synthase (I-PGDS) (5 μM, IR=60 %). mPGES-1-IN-2 reduces PGE2 production and tends to reduce levels of other prostaglandins. mPGES-1-IN-2 effectively inhibits acute inflammation in an air sac model stimulated by Carrageenan (HY-125474) in mice[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C23H34N4O

References: [1]Leclerc P, et al. Characterization of a human and murine mPGES-1 inhibitor and comparison to mPGES-1 genetic deletion in mouse models of inflammation. Prostaglandins Other Lipid Mediat. 2013 Dec;107:26-34.

CAS Number: 1268709-57-4

Molecular Weight: 382.54

Compound Purity: 99.78

Research Area: Endocrinology

Solubility: 10 mM in DMSO

Target: PGE synthase

• Artikelnummer: MEXHY-118282-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-118282-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK