Product Description: Mpro inhibitor N3 is a potent SARS-CoV-2 MPro inhibitor with an EC50 value of 16.77 µM. Mpro inhibitor N3 shows antiviral activities against HCoV-229E, FIPV, IBV and MHV-A59[1][2][3].
Formula: C35H48N6O8
References: [1]Jin Z, et al. Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors. Nature. 2020 Jun;582(7811):289-293./[2]Yang H, et al. Design of wide-spectrum inhibitors targeting coronavirus main proteases. PLoS Biol. 2005 Oct;3(10):e324./[3]Xue X, et al. Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design. J Virol. 2008 Mar;82(5):2515-27.
CAS Number: 884650-98-0
Molecular Weight: 680.79
Compound Purity: 99.96
Research Area: Infection
Solubility: DMSO : 20 mg/mL (ultrasonic)
Target: SARS-CoV;Virus Protease