mTOR inhibitor-16, CAS 1144075-42-2

Product Description: mTOR inhibitor-16 (Compound 9f) is a selective inhibitor for mTOR. mTOR inhibitor-10 inhibits mTOR and PI3K-α, with IC50 of 1.25 and 82 nM. mTOR inhibitor-10 inhibits proliferation of LNCaP with IC50 of 140 nM[1].

Formula: C25H23N5O2S

References: [1]Verheijen JC, et al., Discovery of 2-arylthieno[3,2-d]pyrimidines containing 8-oxa-3-azabi-cyclo[3.2.1]octane in the 4-position as potent inhibitors of mTOR with selectivity over PI3K. Bioorg Med Chem Lett. 2010 Jan 1;20(1):375-9.

CAS Number: 1144075-42-2

Molecular Weight: 457.55

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: mTOR;PI3K

• Artikelnummer: MEXHY-162024-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-162024-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK