Product Description: N6F11 is a ferroptosis inducer, and can trigger the degradation of glutathione peroxidase 4 (GPX4) specifically in cancer cells. N6F11 can be used for ferroptosis study[1].
Applications: Cancer-programmed cell death
Formula: C13H8Cl2N2OS
References: [1]Li J, et al. Tumor-specific GPX4 degradation enhances ferroptosis-initiated antitumor immune response in mouse models of pancreatic cancer. Sci Transl Med. 2023;15(720):eadg3049.
CAS Number: 851398-76-0
Molecular Weight: 311.19
Compound Purity: 98.11
Research Area: Cancer
Solubility: DMSO : 31.25 mg/mL (ultrasonic;warming;heat to 60°C)