Product Description: NA-014 (40) is a selective EAAT2 positive allosteric modulator (PAM), with an EC50 of 3 nM[1].
Applications: Neuroscience-Neuromodulation
Formula: C22H25FN4O
References: [1]Andréia C K Fontana, et al. Synthesis and Structure-Activity Relationships for Glutamate Transporter Allosteric Modulators. J Med Chem. 2024 Apr 25;67(8):6119-6143.