Product Description: Napyradiomycin B4 is a Napyradiomycin derivative, which inhibits the RANKL-induced MEK-ERK signaling pathway. Napyradiomycin B4 attenuates osteoclastogenesis and prevents alveolar bone destruction in experimental periodontitis[1].
Applications: Cancer-Kinase/protease
Formula: C25H31Cl3O6
References: [1]Kim JA, et al., Napyradiomycin B4 Suppresses RANKL-Induced Osteoclastogenesis and Prevents Alveolar Bone Destruction in Experimental Periodontitis. ACS Pharmacol Transl Sci. 2024 Apr 3;7(4):1023-1031.