ND-011992, CAS 2446880-46-0

Product Description: ND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. ND-011992 inhibits respiratory complex I and bo3 oxidase in addition to bd-I and bd-II oxidases in E. coli strain BL21*Δcyo with the IC50 of 0.12, 2.47, 0.63 and 1.3 μM, respectively. ND-011992 can be used for tuberculosis study[1].

Applications: COVID-19-immunoregulation

Formula: C21H14F3N3O

References: [1]Kägi J, et al. Exploring ND-011992, a quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. Sci Rep. 2023;13(1):12226. Published 2023 Jul 28. doi:10.1038/s41598-023-39430-w

CAS Number: 2446880-46-0

Molecular Weight: 381.35

Compound Purity: 98.26

Research Area: Infection

Solubility: DMSO : 40 mg/mL (ultrasonic;adjust pH to 4 with 1 M HCL)

Target: Bacterial;Mitochondrial Metabolism

• Artikelnummer: MEXHY-155107-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-155107-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK