Product Description: NIBR-LTSi is a selective LATS kinase inhibitor and activates YAP signaling. NIBR-LTSi promotes proliferation, maintains stemness, and blocks differentiation. NIBR-LTSi accelerates liver regeneration, following partial and extended hepatectomy[1].
Formula: C18H20N4O
References: [1]Namoto K, et al. NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo. Cell Stem Cell. 2024 Apr 4;31(4):554-569.e17.
Molecular Weight: 308.38
Research Area: Others
Target: YAP