Nicorandil (Standard), CAS 65141-46-0

Product Description: Nicorandil (Standard) is the analytical standard of Nicorandil. This product is intended for research and analytical applications. Nicorandil (SG-75) is a potent potassium channel activator and targets vascular nucleoside diphosphate-dependent K+ channels and cardiac ATP-sensitive K+ channels (KATP). Nicorandil is a nicotinamide ester with vasodilatory and cardioprotective effects and has the potential for angina and forischemic heart diseases[1][2][3].

Formula: N/A

References: [1]Nakae, I., et al., Effects of intravenous nicorandil on coronary circulation in humans: plasma concentration and action mechanism. J Cardiovasc Pharmacol, 2000. 35(6): p. 919-25./[2]Sauzeau, V., et al., Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle. J Biol Chem, 2000. 275(28): p. 21722-9./[3]Mitsuhiko Yamada, et al. The nucleotide-binding domains of sulfonylurea receptor 2A and 2B play different functional roles in nicorandil-induced activation of ATP-sensitive K+ channels. Mol Pharmacol. 2004 May;65(5):1198-207.

CAS Number: 65141-46-0

Molecular Weight: N/A

Research Area: Cardiovascular Disease

Target: Potassium Channel

• Artikelnummer: MEXHY-B0341R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0341R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK