Nifekalant (hydrochloride) (Standard), CAS 130656-51-8

Nifekalant (hydrochloride) (Standard), CAS 130656-51-8
Artikelnummer
MEXHY-B0772AR-0
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MedChemExpress

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Product Description: Nifekalant (hydrochloride) (Standard) is the analytical standard of Nifekalant (hydrochloride). This product is intended for research and analytical applications. Nifekalant hydrochloride (MS-551), a class III antiarrhythmic agent, is a IKr potassium channel blocker with an IC50 of 10 µM. Nifekalant hydrochloride can be used for refractory ventricular tachyarrhythmias research[1][2].

Formula: N/A

References: [1]Lü-Pei Du, et al. The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4771-7./[2]Ioannis N Pantazopoulos, et al. Nifekalant in the treatment of life-threatening ventricular tachyarrhythmias. World J Cardiol. 2011 Jun 26;3(6):169-76./[3]J Chen, et al. IK independent class III actions of MS-551 compared with sematilide and dofetilide during reperfusion in anaesthetized rats. Br J Pharmacol. 1996 Nov;119(5):937-42.

CAS Number: 130656-51-8

Molecular Weight: N/A

Research Area: Cardiovascular Disease

Target: Potassium Channel
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Artikelnummer MEXHY-B0772AR-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-B0772AR-0
Green Labware Nein
Verpackungseinheit Get quote
Mengeneinheit STK
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