Product Description: Nitrefazole is a 4-nitroimidazole derivative with strong and long lasting inhibition of aldehyde dehydrogenase (ALDH), an enzyme involved in the metabolism of alcohol.
Applications: Metabolism-sugar/lipid metabolism
Formula: C10H8N4O4
References: [1]Koda LY, Madamba SG, Bloom FE. Hypotensive response of ethanol in rats pretreated with disulfiram or nitrefazole. Life Sci. 1984;35(16):1659-1665. /[2]Zorzano A, Herrera E. Differences in the kinetic properties and sensitivity to inhibitors of human placental, erythrocyte, and major hepatic aldehyde dehydrogenase isoenzymes. Biochem Pharmacol. 1990;39(5):873-878.
CAS Number: 21721-92-6
Molecular Weight: 248.19
Compound Purity: 99.44
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Aldehyde Dehydrogenase (ALDH)