Product Description: Nitrovin hydrochloride is an antibacterial growth promoter. Nitrovin hydrochloride induces ROS-mediated non-apoptotic and apoptotic-like cell death by targeting TrxR1. Nitrovin hydrochloride has anticancer activity, with IC50 values of 1.31-6.60 μM for tumor and normal cells[1].
Formula: C14H13ClN6O6
References: [1]Zhao L, et al. Nitrovin (difurazone), an antibacterial growth promoter, induces ROS-mediated paraptosis-like cell death by targeting thioredoxin reductase 1 (TrxR1). Biochem Pharmacol. 2023 Apr;210:115487.
CAS Number: 2315-20-0
Molecular Weight: 396.74
Research Area: Cancer; Infection
Solubility: 10 mM in DMSO
Target: Apoptosis;Bacterial;TrxR