NOS1-IN-1, CAS 357965-99-2

Product Description: NOS1-IN-1 is a selective and cell-permeable nNOS inhibitor with a Ki of 120 nM. NOS1-IN-1 exhibits 2617-fold and 325-fold selectivity over eNOS (Ki=39 μM) and iNOS (Ki=325 μM) , respectively[1]. NOS1-IN-1 can be used for the research of neurological disease, including cerebral palsy (CP)[2].

Applications: Neuroscience-Neuromodulation

Formula: C14H24F9N7O8

References: [1]J M Hah, et al. Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoakyl]aminopentyl)-N'-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase. J Med Chem. 2001 Aug 2;44(16):2667-70./[2]Haitao Ji, et al. Selective neuronal nitric oxide synthase inhibitors and the prevention of cerebral palsy. Ann Neurol. 2009 Feb;65(2):209-17.

CAS Number: 357965-99-2

Molecular Weight: 589.37

Compound Purity: 95.0

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: NO Synthase

• Artikelnummer: MEXHY-130452-500UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-130452-500UG
• Green Labware: Nein
• Verpackungseinheit: 500 μg
• Mengeneinheit: STK