NPD10084, CAS 1040706-91-9

Product Description: NPD10084 is a pyruvate kinase PKM2 inhibitor that inhibits non-glycolytic signaling in cancer cells. NPD10084 disrupts the interaction between PKM2 and β-catenin or STAT3 and inhibits downstream signaling. NPD10084 has antiproliferative activity against colorectal cancer cells in vitro and in vivo[1].

Formula: C21H19N3O2

References: [1]Nagasawa I, et al. Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA. Cell Chem Biol. 2020 Feb 20;27(2):186-196.e4.

CAS Number: 1040706-91-9

Molecular Weight: 345.39

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Pyruvate Kinase

• Artikelnummer: MEXHY-148615-50
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-148615-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK