Product Description: NPP1-IN-2 (compound 3h) is a potent and selective Ectonucleotide pyrophosphatase/phosphodiesterase-1 (NPP1) inhibitor with IC50 values of 0.55, 3.73 µM for NPP1, NPP3, respectively[1].
Formula: C22H22N4OS
References: [1]Tasleem M, et al. Synthesis, in vitro, and in silico studies of morpholine-based thiosemicarbazones as ectonucleotide pyrophosphatase/phosphodiesterase-1 and -3 inhibitors. Int J Biol Macromol. 2024 Mar 24;266(Pt 2):131068.
Molecular Weight: 390.50
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Phosphatase