ODN 2336 (sodium)

Product Description: ODN 2336 sodium is a A-Class CpG ODN (oligodeoxynucleotides), is a potent TLR9 agonist. ODN 2336 sodium induces the production of IFN-α. ODN 2336 sodium up-regulates the expression of IP-10 mRNA and IL-18 mRNA. ODN 2336 sodium can be used as adjuvant of vaccines[1][2][3].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]urk M, et al. C-Class CpG ODN: sequence requirements and characterization of immunostimulatory activities on mRNA level. Immunobiology. 2004;209(1-2):141-54. /[2]old MC, et al. Purified neonatal plasmacytoid dendritic cells overcome intrinsic maturation defect with TLR agonist stimulation. Pediatr Res. 2006 Jul;60(1):34-7./[3]Hilbert T, et al. Beta2-adrenoceptor stimulation suppresses TLR9-dependent IFNA1 secretion in human peripheral blood mononuclear cells. PLoS One. 2013 May 28;8(5):e65024.

Molecular Weight: N/A

Compound Purity: 90.74

Research Area: Inflammation/Immunology

Solubility: 10 mM in H2O

Target: Toll-like Receptor (TLR)

• Artikelnummer: MEXHY-150742A-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-150742A-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK