Product Description: Oligomycin E is a antitumor antibiotic that can be isolated from Streptomyces. Oligomycin E has significant antifungal activity, showing minimal inhibitory concentrations (MICs) values between 2 and 75μg/mL. Oligomycin E has strong antitumor activity against HeLa cells, with an IC50 of 0.014 μg/mL[1].
Formula: C45H72O13
References: [1]Kobayashi K, et al. Oligomycin E, a new antitumor antibiotic produced by Streptomyces sp. MCI-2225. J Antibiot (Tokyo). 1987 Jul;40(7):1053-7./[2]Khebizi N, et al. Oligomycins A and E, major bioactive secondary metabolites produced by Streptomyces sp. strain HG29 isolated from a Saharan soil. J Mycol Med. 2018 Mar;28(1):150-160.
CAS Number: 110231-34-0
Molecular Weight: 821.05
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Antibiotic;Fungal