Oteseconazole (Standard), CAS 1340593-59-0

Product Description: Oteseconazole (Standard) is the analytical standard of Oteseconazole. This product is intended for research and analytical applications. Oteseconazole (VT-1161) is a potent and orally active anti-fungal agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity (Kd ≤39 nM), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes[1][2].

Formula: N/A

References: [1]Warrilow AG, et al. The clinical candidate VT-1161 is a highly potent inhibitor of Candida albicans CYP51 but fails to bind the human enzyme. Antimicrob Agents Chemother. 2014 Dec;58(12):7121-7./[2]Garvey EP, et al. VT-1161 dosed once daily or once weekly exhibits potent efficacy in treatment of dermatophytosis in a guinea pig model. Antimicrob Agents Chemother. 2015 Apr;59(4):1992-7.

CAS Number: 1340593-59-0

Molecular Weight: N/A

Research Area: Infection

Target: Cytochrome P450;Fungal

• Artikelnummer: MEXHY-17643R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-17643R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK