PDDHV, CAS 179469-40-0

Product Description: PDDHV is a calcium absorption inducer and may achieve 45Ca2+ influx by stimulating vanillic acid receptor VR1. PDDHV induces 45Ca2+ uptake (EC50: 70 nM) in rat dorsal root ganglion neurons (expressing native vanilloid receptors) and calcium mobilization (EC50: 125 nM) in VR1-transfected CHO cells. PDDHV also inhibits [3H]-resiniferatoxin (RTX) binding to the dorsal root ganglion membrane in rats[1].

Formula: C49H72O11

References: [1]Szallasi A, Szabo T, Biro T, et al. Resiniferatoxin‐type phorboid vanilloids display capsaicin‐like selectivity at native vanilloid receptors on rat DRG neurons and at the cloned vanilloid receptor VR1[J]. British journal of pharmacology, 1999, 128(2): 428-434.

CAS Number: 179469-40-0

Molecular Weight: 837.09

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Calcium Channel

• Artikelnummer: MEXHY-130358-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-130358-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK