Pemetrexed (disodium) (Standard), CAS 150399-23-8

Product Description: Pemetrexed (disodium) (Standard) is the analytical standard of Pemetrexed (disodium). This product is intended for research and analytical applications. Pemetrexed disodium (LY231514 disodium) is an antifolate, the Kis of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively[1].

Formula: N/A

References: [1]Shih C, et al. LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes. Cancer Res. 1997 Mar 15;57(6):1116-23./[2]Anraku M, et al. Synergistic antitumor effects of regulatory T cell blockade combined with pemetrexed in murine malignantmesothelioma. J Immunol. 2010 Jul 15;185(2):956-66.

CAS Number: 150399-23-8

Molecular Weight: N/A

Research Area: Cancer

Target: Antifolate;Apoptosis;Autophagy

• Artikelnummer: MEXHY-10820AR-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-10820AR-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK