PF-04822163, CAS 1798334-07-2

Product Description: PF-04822163 is an orally active, selective, and blood-brain barrier permeable PDE1 inhibitor with IC50 values of 2 nM, 2.4 nM, and 7 nM for PDE1A, PDE1B, and PDE1C respectively. PF-04822163 can be used in the research of attention deficit hyperactivity disorder or Parkinson's disease[1].

Formula: C19H17ClN2O2

References: [1]Humphrey J M, et al. Small-molecule phosphodiesterase probes: discovery of potent and selective CNS-penetrable quinazoline inhibitors of PDE1[J]. MedChemComm, 2014, 5(9): 1290-1296.

CAS Number: 1798334-07-2

Molecular Weight: 340.80

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Phosphodiesterase (PDE)

• Artikelnummer: MEXHY-120741-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-120741-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK