Product Description: PHD2-IN-2 (Compound 12) is a PHD2 inhibitor, with an IC50 of 34.3 nM. PHD2-IN-2 has high erythropoietin (EPO) inducing activity, with an EC50 of 6.79 μM. PHD2-IN-2 can be used for the research of anemia, ischemia, and hypoxia[1].
Formula: C19H18N4O4
References: [1]Tang HT, et al. Prolyl hydroxylase inhibitor and use thereof. WO2024061172A1.
Molecular Weight: 366.37
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: HIF/HIF Prolyl-Hydroxylase