Phenylbutazone (Standard), CAS 50-33-9

Product Description: Phenylbutazone (Standard) is the analytical standard of Phenylbutazone. This product is intended for research and analytical applications. Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research[1][2].

Formula: N/A

References: [1]Beretta C, et al. COX-1 and COX-2 inhibition in horse blood by phenylbutazone, flunixin, carprofen and meloxicam: an in vitro analysis. Pharmacol Res. 2005 Oct;52(4):302-6./[2]G A Reed, et al. Inactivation of prostaglandin H synthase and prostacyclin synthase by phenylbutazone. Requirement for peroxidative metabolism. Mol Pharmacol. 1985 Jan;27(1):109-14./[3]Guiying Chen, et al. Phenylbutazone induces expression of MBNL1 and suppresses formation of MBNL1-CUG RNA foci in a mouse model of myotonic dystrophy. Sci Rep. 2016 Apr 29;6:25317.

CAS Number: 50-33-9

Molecular Weight: N/A

Research Area: Inflammation/Immunology

Target: COX

• Artikelnummer: MEXHY-B0230R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0230R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK