PHGDH-IN-5, CAS 17402-86-7

Product Description: PHGDH-IN-5 (Compound B12) is a covalen inhibitor of PHGDH with an IC50 value of 0.29 μM. PHGDH-IN-5 can inhibit cell proliferation in cancer cell lines overexpressing PHGDH. PHGDH-IN-5 can reduce the production of serine derived from glucose in MDA-MB-468 cells[1].

Formula: C8H5NO4S

References: [1]Cao XY, et al. Identification of benzo[b]thiophene-1,1-dioxide derivatives as novel PHGDH covalent inhibitors. Bioorg Chem. 2024;146:107330.

CAS Number: 17402-86-7

Molecular Weight: 211.19

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Phosphoglycerate Dehydrogenase (PHGDH)

• Artikelnummer: MEXHY-161456-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161456-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK