PhIP, CAS 105650-23-5

Product Description: PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) is the most abundant of generation of heterocyclic amines (HCA), resulted in the cooking of meat[1][2]. DNA damaging and mutagenic activities. PhIP also has oestrogenic activity that could contribute to its tissue specific carcinogenicity[2].

Applications: Cancer-programmed cell death

Formula: C13H12N4

References: [1]Bellamri M, et al. Metabolic Activation of the Cooked Meat Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine in Human Prostate. Toxicol Sci. 2018 Jun 1;163(2):543-556./[2]Papaioannou MD, et ak. The cooked meat-derived mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) elicits estrogenic-like microRNA responses in breast cancer cells. Toxicol Lett. 2014 Aug 17;229(1):9-16.

CAS Number: 105650-23-5

Molecular Weight: 224.26

Compound Purity: 99.85

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Others

• Artikelnummer: MEXHY-118716-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-118716-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK