Product Description: PIP5K1C-IN-1 (Compound 30) is a potent PIP5K1C inhibitor, with an IC50 of 0.80 nM. PIP5K1C-IN-1 exhibits low total clearance in mice and high levels of kinase selectivity. PIP5K1C-IN-1 can be used for the research of cancer and chronic pain[1].
Formula: C20H20ClN5O
References: [1]Ochiai K, et al. Discovery of Novel Bicyclic Pyrazoles as Potent PIP5K1C Inhibitors. ACS Medicinal Chemistry Letters, 2024.